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Explanation of the table: Summaries of national and multi-national approvals of genetically engineered products

Table 4: Genetically engineered products approved for food use in the United Kingdom

Product
Name
Company
Altered trait # Promoter
Genes introduced
(Sources of transgenes)
Terminator Approval / Date Related approvals country (ID) ID
Chymosin***
(ex K. lactis)
Maxiren®
Giste Brocades
Cheese
production
nda
bovine prochymosin (isomer B)
(bovine)
ndaMAFF: 1/91alpha37
Chymosin***
(ex E. coli K12)
Chy-Max®
Pfizer
Cheese
production
nda
bovine prochymosin (isomer A)
(bovine)
ndaMAFF: 3/92alpha38
Chymosin***
(ex A. niger)
Chymogen®
Christian Hansen / Genencor
Cheese
production
nda
bovine prochymosin (isomer B)
(bovine)
ndaMAFF: 5/91alpha 39
Riboflavin (Vit. B2)
(ex B.subtilis RB50)
Hoffmann-La Roche
Food
additive
1) bacteriophage SP01

2) nda

3) nda

riboflavin operon (5 genes)
(Bacillus subtilis)
tet
(Bacillus cereus)
cat
(Staphylococcus aureus)
bacterial

nda

nda

MAFF: 1/97-
Corn
(for processing only)
Maximizer®
Ciba-Geigy Ltd.
IR (L)
HT (pt)
1) P-PEPC and P-CDPK

2) P-35S

3) bacterial

synthetic, truncated cryIA(b) delta-endotoxin
(Bt ssp. kurstaki (HD-1))
bar
(Streptomyces hygroscopicus)
bla
(Tn3)
I9, T-35S

I9, T-35S

bacterial

MAFF: 5/96US (14, 61),
Can (74), Jap (87),
EC (-)
41
Corn
AgrEvo
HT (pt)1) P-35S

2) bacterial

synthetic pat
(Streptomyces viridochromogenes)
bla (incomplete)
(E. coli (Tn3))
T-35

bacterial

MAFF: 2/97US (15) -
Corn
Monsanto§
IR (L)1) P-35S, m-HSP70-utr§
synthetic, truncated cryIA(b) delta-endotoxin§
(Bt ssp. kurstaki§)
nos 3'§MAFF: 2/97US (18), UK (-) -
Corn
Northrup King
IR (L)
HT (pt)
1) P-35S with IVS6-utr

2) P-35S with IVS2-utr

synthetic, truncated cryIA(b) delta-endotoxin
(Bt ssp. kurstaki (HD-1))
synthetic pat
(Streptomyces viridochromogenes)
nos 3'MAFF: 2/97US (20), Can (79), Jap (84) -
Corn
Pioneer HI-Bred Int. (under license
from Monsanto)
IR (L)
HT (gly)
1) P-35S, m-HSP70-utr

2) P-35S, m-HSP70-utr

3) P-35S, m-HSP70-utr

4) bacterial

synthetic cryIA(b) delta-endotoxin
(Bt ssp. kurstaki (HD-1))
CP4 epsps (with CTP2)
(Agrobacterium (Arabidopsis))
gox with CTP1 (incomplete)
(Achromobacter sp. (Arabidopsis))
nptII
(E. coli (Tn5) )
nos 3'

nos 3'

nos 3'

bacterial

MAFF: 2/97US (18), UK (-) -
Cotton (oil)
BXN cotton®
Calgene /
Rhône-Poulenc
HT (br)1) P-35S

2) P-35S

BXN gene (nitrilase)
(Klebsiella ozaenae)
nptII
(E. coli (Tn5) )
tml 3'

tml 3'

MAFF: 1/97US (7) , Can (80) -
Oilseed rape / canola (for processing only)
AgrEvo
HT (pt)1) P-35S

2) P-nos

synthetic pat
(Streptomyces viridochromogenes)
nptII
(Tn5)
T-35S

ocs 3'

MAFF: 5/95US (66), Can (69), Jap (85)47
Oilseed rape / canola (for processing only)
Roundup Ready®
Monsanto
HT (gly)1) P-FMV

2) P-FMV

synthetic CP4 epsps (with CTP2)
(Agrobacterium (Arabidopsis))
synthetic , slightly altered gox (with CTP1)
(Achromobacter (Arabidopsis))
E9 3'

E9 3'

MAFF: 1/96US (65) Can (68), Jap (82)48
Oilseed rape / canola (for processing only)
Plant Genetic Systems
MS
HT (pt)
1) P-TA29 (ts, dr)

2) P-TA29 (ts, dr)

3) P-SsuAra

4) P-nos

barnase
(Bacillus amyloliquefaciens)
barstar
(Bacillus amyloliquefaciens)
bar (with CTP)
(Streptomyces hygroscopicus)
nptII
(Tn5)
nos 3'

nda

Tr7 3'

ocs 3'

MAFF: 2/95, 9/95US (60), EC (33),
Jap (86),
Can (67, 71)
45

46

Soybean
(for processing only)
Roundup Ready®
Monsanto
HT (gly)1) e-P-35S
CP4 epsps (with CTP4)
(Agrobacterium (Petunia hybrida))
nos 3'MAFF: 2/95US (8), EC (34), NL (98), Can (75), Jap (81), CH/Aus (-)52
Tomato
Flavr SavrTM
Calgene
PQ (frd)1) d-P-35S

2) mas 5'

3) -

polygalacturonase (antisense)
(Tomato)
nptII
(Tn5)
LacZ (incomplete)
(E. coli)
tml 3'

mas 3'

-

MAFF: 2/96US (1), Can (70)53
Tomato (processed)
Sainsbury's, Safeway
Zeneca
PQ (frd)1) P-35S

2) P-nos

3) -

truncated polygalacturonase (sense)
(Tomato)
nptII
(bacterial)
fragments of ocd, M13 geneIII and LacZ
(A. tumefaciens, M13, E. coli)
nos 3'

nos 3'

-

MAFF: 2/95

,2/96

US (12), Can (78)51

54

Yeast (bakers')
Giste Brocades
Carbo-
hydrate
metabolism
1) P-EF(A

2) P-adh I

maltase
(Yeast)
maltose permease
(Yeast)
nda

nda

MAFF: 2/9049
Yeast (brewers')
BFR International
Improved
starch
degradation
1) nda

2) nda

STA2
(Yeast)
CUP1
(Yeast)
nda

nda

MAFF: 3/9450

Primary source: MAFF; italics, data given in italics were taken from sources other than the responsible approving authorities (e.g. description of a related product); §, transformed with the same plasmid that was used for ID 18; ***) prochymosin is purified and activated to chymosin by autocatalysis at pH 2; alpha, recombinantly expressed chymosin has been approved in at least 17 countries (see , legend of Table 6 [Approved genetically engineered food products in Switzerland]); for explanations and abbreviations see legend of Table 3 (Approved genetically modified crops in the United States) and Glossary.


© Copyright Agency BATS: Contact Legal Advisor: Advokatur Prudentia-Law Date of publishing: 1997-02-08

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